RSS Feed

Posted on 01-18-2013

Good Morning Friends!

 The Cochrane Library is the worlds best collection of studies known as Randomized Controlled Clinical Trials (RCT).  What they do is they create a synthesis of the worlds best medical research and compile the final results.  Keep in mind over 1,200 research studies go into the scientific literature every day!!  You can view them at pubmed.gov.  But that said this latest from the Cochrane library looks at the effects both good and bad for the flu shot!  Ready the short abstract below and I will comment at the bottom:

Background: 

Different types of influenza vaccines are currently produced worldwide. Healthy adults are presently targeted mainly in North America.

Objectives: 

Identify, retrieve and assess all studies evaluating the effects of vaccines against influenza in healthy adults.

Search strategy: 

We searched the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library, 2010, issue 2), MEDLINE (January 1966 to June 2010) and EMBASE (1990 to June 2010).

Selection criteria: 

Randomised controlled trials (RCTs) or quasi-RCTs comparing influenza vaccines with placebo or no intervention in naturally-occurring influenza in healthy individuals aged 16 to 65 years. We also included comparative studies assessing serious and rare harms.

Data collection and analysis: 

Two review authors independently assessed trial quality and extracted data.

Main results: 

We included 50 reports. Forty (59 sub-studies) were clinical trials of over 70,000 people. Eight were comparative non-RCTs and assessed serious harms. Two were reports of harms which could not be introduced in the data analysis. In the relatively uncommon circumstance of vaccine matching the viral circulating strain and high circulation, 4% of unvaccinated people versus 1% of vaccinated people developed influenza symptoms (risk difference (RD) 3%, 95% confidence interval (CI) 2% to 5%). The corresponding figures for poor vaccine matching were 2% and 1% (RD 1, 95% CI 0% to 3%). These differences were not likely to be due to chance. Vaccination had a modest effect on time off work and had no effect on hospital admissions or complication rates. Inactivated vaccines caused local harms and an estimated 1.6 additional cases of Guillain-Barré Syndrome per million vaccinations. The harms evidence base is limited.

Authors' conclusions: 

Influenza vaccines have a modest effect in reducing influenza symptoms and working days lost. There is no evidence that they affect complications, such as pneumonia, or transmission.

WARNING:
This review includes 15 out of 36 trials funded by industry (four had no funding declaration). An earlier systematic review of 274 influenza vaccine studies published up to 2007 found industry funded studies were published in more prestigious journals and cited more than other studies independently from methodological quality and size. Studies funded from public sources were significantly less likely to report conclusions favorable to the vaccines. The review showed that reliable evidence on influenza vaccines is thin but there is evidence of widespread manipulation of conclusions and spurious notoriety of the studies. The content and conclusions of this review should be interpreted in light of this finding.

This record should be cited as: 

Jefferson T, Di Pietrantonj C, Rivetti A, Bawazeer GA, Al-Ansary LA, Ferroni E. Vaccines for preventing influenza in healthy adults. Cochrane Database of Systematic Reviews 2010, Issue 7. Art. No.: CD001269. DOI: 10.1002/14651858.CD001269.pub4

Folks, what this tells us is the flu shot even with its risks and harms having "limited" research, is just not worth the 3% improvement in your chances of getting the flu.  Flu shots still largely have mercury in them known as thimerosol, plus a host of other ingredients that you just don't want in your body (e.g. anti-freeze).  If you really want to avoid the flu, take plenty of Vitamin D3, reduce or eliminate grains and sugar from your diet, get adjusted in the upper neck to stimulate your immune function, and practice sanitary hygiene.  

Have a blessed weekend!

MERB50.Meredity.Email.Signature.jpg

There are no comments for this post. Please use the form below to post a comment.

To leave a comment, please login as a member

Contact

Get Directions
 
WellnessOne of Redding
2515 Park Marina Drive, Suite 101
Redding, CA 96001
Get Directions
  • Phone: 530-243-9464
  • Fax: 530-243-9499
  • Email Us

Office Hours

DayMorningAfternoon
Monday8:30 - 1:003:00 - 6:00
Tuesdayclosed3:00 - 6:00
Wednesday8:30 - 1:003:00 - 6:00
Thursdayclosed3:00 - 6:00
Friday8:30 - 1:00By Appt
Saturdayclosedclosed
Sundayclosedclosed

Featured Articles

Newsletter Sign Up